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Ts'ebetso e ncha ea lipatlisiso ka gallic acid

6ba5b362475a44a843bb9439767aa57f1. Phello e khahlanong le hlahala

1) Thibela ho thehoa ha hlahala;ho thehoa ha hlahala ke mokhoa oa ho fetola liphatsa tsa lefutso tse ngata, tse nang le mehato e mengata.Hoa tsebahala hore lik'hemik'hale tse ngata tsa lik'hemik'hale li ka susumetsa le ho khothalletsa ho thehoa ha hlahala, 'me gallic acid e na le liphello tse thibelang le tse thibelang mehato eohle ea ho thehoa ha hlahala.Gallic acid e ka thibela phello e khothalletsang mofets'e ea guanylate decarboxylase (ODC).

2) Cytotoxicity: Gallic acid e ka thibela le ho bolaea lisele tsa hlahala ka ho toba.Ha ho hlahlojoa lithethefatsi tse khahlanong le hlahala ka mekhoa ea meriana ea setso ea Sechaena, ho ile ha fumanoa hore ha IC e ne e le 4.8 ~ 13,2ml, GA e bontšitse liphello tsa cytotoxic ho li-hepatocyte tsa rat le macrophages, 'me li bontša li-fibroblasts le lisele tsa endothelial.Cytotoxicity e nyane.

3)) Thibelo ea tumor angiogenesis: Angiogenesis ke ts'ebetso ea bohlokoa ea mafu ho kholo ea hlahala le metastasis, 'me ts'ebetso, ho ata, ho falla le ho thehoa ha li-tubule tsa vascular endothelial cell (VEC) ke mehato ea eona ea bohlokoa.Boithuto bona bo fumane hore gallic acid e thibela kholo ea methapo ea mali ea hlahala ka lebaka la litlamorao tsa synergistic kapa tse matla tse susumetsang lipakeng tsa asiti ea gallic le li-extracts tse ling tse sa netefatsoang, e fana ka maikutlo a hore ho na le mofuta oa dosing oa tlhaho le o laoloang habonolo, hape le bakeng sa ntlafatso ea anti-VEC ea gallic acid.Fana ka bopaki ba kliniki.

4) Joalo ka ntho ea polyphenolic, GA e na le litlamorao tse matla tsa antioxidant le anti-free radical.Tšenyo ea oxidative le e sa lefelloeng ea radical e amoheloa e le e 'ngoe ea mekhoa ea bohlokoa e bakang tšenyo ea lisele tsa DNA mme e lebisa ho mpeng ea lisele.

5) Induction ea tumor cell apoptosis: litlaleho tsa lipatlisiso li bonts'a hore kutlo ea GA ho susumetsa apoptosis ha e fetohe le cisplatin resistance, e bonts'a hore GA e ka sebelisoa kalafong ea mofets'e oa matšoafo, haholo mofets'e oa matšoafo o hananang le lithethefatsi tse thibelang hlahala.

2. Liphello sebeteng

Bafuputsi ba Machaena ba lumela hore GA e na le phello ea anti-HBV.Anti-Hepatitis B Virus Surface Antigen (HBSAg) le Hepatitis B Virus e Antigen (HBeAg) li ile tsa ithutoa ka liteko, ho sebelisoa theknoloji ea enzyme-linked immunosorbent assay (ELISA) ho khetha mefuta e 4 ea GA, Yunzhi Gantai, Yigan Granule le Yiganning Drug efficacy test. .GA ke setlhare se sebetsang khahlano le HBSAg/HBeAg se hlahlobiloeng ka laboratoring.

3. Phello ea methapo ea mali

Ho ile ha ithutoa phello ea vascular ea GA ho urine thoracic aorta, 'me ho ile ha bontšoa hore GA e ne e e-na le phello ea vasoconstrictive ho methapo e tsitsitseng e tsitsitseng e tšoaroang ka phenylephrine kapa prostaglandin F (2/), ha GA e ne e se na phello ea vasoconstrictive ho endothelial e hlobotseng. methapo ea mali.

4. Thibelo le kalafo ea AIDS

Gall tannins ke esters ea gallic acid le polyols tse kang glucose, quinic acid, shikimic acid, joalo-joalo Mefuta e tloaelehileng ea gallic tannins ke: tannins (Chinese gall tannins), shirataki tannins le tara tannins.Hangata li-tannins tsa nyooko ke motsoako oa li-ester tse nang le likhato tse fapaneng tsa ho imena habeli.Gallotannin ke mofuta o ka sehloohong oa tannin o sebelisoang liphuputsong tse khahlanong le HIV.

5. Ketso ea trypanicidal

Liboko tsa bohlokoa tsa Afrika ke likokoana-hloko tsa protozoan tse ka bakang tšitiso ea boroko ho batho le liphoofolo.

6. Bakeng sa liphello tse khahlanong le ho ruruha, bacteriostatic le antiviral

Liphello tse khahlanong le ho ruruha le bacteriostatic tsa gallic acid li ile tsa ithutoa, 'me ho ile ha bontšoa hore gallic acid e na le liphello ho ruruha ha lenonyeletso la rat e bakoang ke lehe le lesoeu, dextran, 5-hydroxytryptamine le formaldehyde, tse emelang ho ruruha ho matla.E na le phello e kholo ea anti-inflammatory;nka tekanyo e itseng ea gallic acid, eketsa metsi ho sila le ho qhibiliha, 'me ue kenye ho 9ml agar medium.Gallic acid e na le phello e matla ea thibelo ho Escherichia coli, Staphylococcus aureus, Pasteurella, le Streptococcus.Ts'ebetso ea kokoana-hloko e khahlanong le NDV ea karolo e sebetsang ea monomer gallic acid ka tee ea Pu-erh e ile ea khethoa ke mokhoa oa cytopathic.Liphetho li bonts'a hore asiti ea gallic e na le ts'ebetso ea kokoana-hloko ea anti-NDV.Liteko tse sebelisang mefuta ea lisele ho hlahloba phello ea gallic acid ho li-receptor tsa PPAK


Nako ea poso: Jul-08-2022